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Writer's pictureYaopeng Zhou

Colchicine And CPPD

Started my first patient on colchicine. She is an ideal candidate: 69 yo female with non-obstructive LAD lesion with  CPPD athropathy, LDL-C 53 HDL-C 92 but CRP 7 on a statin.




calcium pyrophosphate dihydrate, Colchicine

Colchicine is a medication commonly used to treat gout and other inflammatory conditions. It works by reducing the inflammation caused by the deposition of urate crystals in the joints. In this case, colchicine is being used to manage CPPD (calcium pyrophosphate dihydrate) arthropathy, which is a type of arthritis caused by the accumulation of calcium pyrophosphate crystals in the joints. The patient's age, gender, and medical history make her an ideal candidate for colchicine therapy. However, it is important to monitor her liver and kidney function regularly, as colchicine can have side effects on these organs.




1. The clinical criteria or approval criteria or medical necessity for starting a patient on colchicine in this case would include the following factors:

- Age: The patient is 69 years old, which falls within the typical age range for colchicine therapy.

- Diagnosis: The patient has non-obstructive LAD lesion with CPPD arthropathy, which is an indication for colchicine treatment.

- Lipid levels: The patient has LDL-C of 53 and HDL-C of 92, which are within normal ranges.

- CRP level: The patient has a CRP level of 7, indicating inflammation despite being on a statin. This further supports the need for colchicine therapy.



2. A claim for colchicine treatment in this case is unlikely to be denied because the patient meets the clinical criteria and medical necessity for the treatment. The patient's age, diagnosis, and lipid levels all align with the indications for colchicine therapy. Additionally, the elevated CRP level suggests ongoing inflammation that may not be adequately controlled by statin therapy alone. Therefore, starting the patient on colchicine is justified based on her clinical profile. However, it is important to note that individual insurance policies and coverage may vary, so it is always advisable to check with the specific insurance provider regarding coverage and potential denials.


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